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Since tropomyosins organize actin filaments and stabilize stress fibers, which are the primary structures sensing mechanical cues, we propose that tropomyosins may be involved in the fibroblasts ability to sense and respond to increased tissue stiffness

Parkin, encoded by PRKN, functions in conjunction with PINK1, a mitochondrial-targeted serine kinase

[203] reported a pH-responsive surface-functionalized mesoporous silica nanoparticle system for simultaneously delivering both growth factor bone morphogenetic protein-2 and the drug dexamethasone for osseointegration

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