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61 AN OPEN-LABEL ROLLOVER STUDY FOLLOWING A RANDOMIZED TRIAL FOR CHRONIC HEPATITIS B WITH HIGH SERUM VIRAL LOAD BUT MILD ELEVATED AMINOTRANSFERASE Yao-Chun Hsu 1 , Chi-Yi Chen 2 , Cheng-Hao Tseng 3 , Chieh-Chang Chen 4 , Teng-Yu Lee* 5 , Ming-Jong Bair 6 , Jyh-Jou Chen 7 , I-Wei Chang 8 , CHi-Yang Chang 9 , Ming-Shiang Wu 10 and Jaw-Town Lin 1 , (1)E-Da Hospital, (2)Ditmanson Medical Foundation Chiayi Christian Hospital, Chia Yi, Taiwan, (3)E-Da Cancer Hospital, I-Shou University, (4)National Taiwan University Hospital, (5)Taichung Veterans General Hospital, (6)Mackay Memorial Hospital-Taitung, (7)Department of Internal Medicine, Chi Mei Medical Center, Liouying, Tainan, Taiwan, (8)Taipei Medical Universtiy, (9)Fu-Jen Catholic University, (10)Tainan Municipal Hospital Background: This study extends the follow-up of participants who completed a randomized placebo-controlled trial evaluating the safety and efficacy of tenofovir disoproxil fumarate (TDF) in reducing the risk of histological progression in patients with chronic hepatitis B (CHB) characterized by high viral load and minimally raised serum alanine aminotransferase (ALT) levels

Our findings suggest that GSH depletion induces ferroptosis, autophagy, and SIPS

Gold nanostars loaded with triamcinolones, when coupled with MSC to promote the repolarization of macrophages, can inhibit the Th17 differentiation and induce the regeneration of cartilage (105)

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