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They remind your cells how to do things they already know how to do, but may have forgotten or gotten sluggish about due to aging, stress, or damage

doi: 10.1016/j.pccm.2023.10.001 68 GaoJShenYChenZ

Abbreviations MetS: Metabolic syndrome T2DM: Type 2 diabetes mellitus NAFLD: Nonalcoholic fatty liver disease CVD: Cardiovascular disease RCT: Randomized controlled trial BMI: Body mass index HOMA: IRHomeostatic model assessment of insulin resistance HbA1c: Glycated hemoglobin LDL: Lowdensity lipoprotein HDL: Highdensity lipoprotein TG: Triglycerides SBP: Systolic blood pressure DBP: Diastolic blood pressure ROS: Reactive oxygen species NF: BNuclear factor kappa B AMPK: Adenosine monophosphateactivated protein kinase PPAR: Peroxisome proliferatoractivated receptor GRADE: Grading of Recommendations Assessment, Development and Evaluation CONSORT: Consolidated Standards of Reporting Trials PRISMA: Preferred Reporting Items for Systematic Reviews and MetaAnalyses ALT: Alanine aminotransferase AST: Aspartate aminotransferase CRP: Creactive protein References Macut D, Ognjanovi S, Aanin M, Krljana G, Milenkovi T