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The most important non-protein thiol source in intermediary metabolism is glutathione (GSH, containing a single cysteine moiety) and the small protein thioredoxin (containing two redox-active half-cysteine residues

doi: 10.1007/s00204-011-0674-5 Summary Keywords epigenetic regulation, KEAP1/Nrf2/HO-1 signaling, MAPKAPK2, oxidative stress, vitiligo Citation Wang Y and Zheng X (2026) Epigenetic downregulation of MAPKAPK2 exacerbates oxidative stress-induced damage in vitiligo melanocyte cell line model