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An elevated level of macroautophagy has been noted during the advancement of MSA, hinting at a potential involvement in eliminating protein clumps [314]

Human frataxin activates FeS cluster biosynthesis by facilitating sulfur transfer chemistry

3.2 Metalloproteinase Tamoxifen successfully up-regulated expression of metalloproteinases-1, TIMP-1, and down-regulated expression of matrix metalloproteinase 9, MMP-9