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The implication is that theyre roughly the same kind of thing and youre choosing between them

151 Activated AKT can phosphorylate and inhibit TSC2, which regulates translation, transcription, and other cellular processes by removing the inhibition of mTORC1 by the TSC1/2 complex and promoting mTORC1 activity

The predictors of pemetrexed toxicities were poor Eastern Cooperative Oncology Group performance status (ECOG-PS) and low body mass index (BMI) for febrile neutropenia (FN), concomitant chronic infectious disease, bevacizumab use for neutropenia, poor ECOG-PS for thrombocytopenia, and low serum albumin levels for non-hematologic toxicities

This makes some sense, as it can survive at least 24 hours in gastric acids (which is where it normally lives)