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Spread of infection Strep bacteria may spread, causing infection in: Tonsils Sinuses Skin Blood Middle ear Inflammatory reactions Strep infection may lead to inflammatory illnesses, including: Scarlet fever, a streptococcal infection characterized by a prominent rash Inflammation of the kidney (poststreptococcal glomerulonephritis) Rheumatic fever, a serious inflammatory condition that can affect the heart, joints, nervous system and skin Poststreptococcal reactive arthritis, a condition that causes inflammation of the joints A possible relationship has been suggested between strep infection and a rare condition called pediatric autoimmune neuropsychiatric disorder associated with group A streptococci (PANDAS)

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