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and a 2021 peer-reviewed review on NNMT in obesity and type 2 diabetes noting the absence of human clinical trials

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Comment: Several commenters supported the proposal to strengthen the current HPT requirements by replacing the affirmation standard with a more robust attestation. These commenters agreed that hospitals should attest that they have included all applicable payer-specific negotiated charges that can be expressed in dollars, and for charges not knowable in advance or that cannot be expressed as a dollar amount, hospitals should be required to include in the MRFs all necessary information available to enable the public to derive the dollar amountsuch as the specific fee schedule or components referenced in any percentage, algorithm, or formula

For instance, if you reconstitute a 12 mg vial with 2.4 mL of BAC water, the concentration becomes 5 mg per mL