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poxviruses encode many proteins which interact with host processes at both cellular and systemic levels some of which blocked the development of a chemotactic substance, or interfered with the activation of the classical complement pathway

The two main sources of intracellular Fe 2 + accumulation during ferroptosis are: (1) TF binds to TFR and enters the cell, where the low pH value promotes the release of Fe3 + from TF, which is then reduced to Fe 2 + in the cytoplasm

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