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Moderate deficiency may include obvious macrocytic anemia, glossitis, as well as some mild or subtle neurological features, such as distal sensory impairment.[] Severe deficiency is characterized by bone marrow suppression, neurological features, and the risk of cardiomyopathy

They are widely present in eukaryotes, and their dysregulation is closely associated with the occurrence and progression of various diseases (Wu et al., 2014)

Discussion The RNA helicase DDX3X has primarily been associated with cellular RNA metabolism, the interferon response and modulation of RNA viruses

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