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Javitt DC, Zukin SR, Heresco-Levy U, Umbricht D

Adopting a microinjection approach to isolate GSSG elevation within the cell, this work identifies that GSSG can trigger neural HT4 cell death via a 12-lipoxygenase (12-Lox)-dependent mechanism

Moreover, the substrate specificities of Na + -LNAA and SBAT1 are not the same ( Transport of Small Non-essential Neutral AAs: System A Alanine, serine and cysteine can be transported by the sodium-dependent system A (named A for its preference for Ala as a substrate)