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2286-C CircZBTB46 ALLEVIATES NON-ALCOHOLIC FATTY LIVER DISEASE BY TARGETING MIR-326/FGF1/AMPK AXIS Qingmin Zeng 1 , Chang-Hai Liu 1 , Wei Jiang 1 , Dongbo Wu 1 and Hong Tang 2 , (1)West China Hospital, Sichuan University, (2)West China Hospital of Sichuan University Background: Non-alcoholic fatty liver disease (NAFLD) is currently the most prevalent cause of chronic liver diseases worldwide