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Results indicated that the permeability over human skin was -6.28, -5.62, and -6.14 cm/s for curcumin, capsaicin, and gingerol, respectively

The FDA has indicated it will remove the seven compounds from the interim Category 2 restricted list while the July review proceeds

doi: 10.1080/17518253.2023.2275666 273 ScheenAJDelanayeP

3.2.1 Non-dopaminergic Drugs to Treat Levodopa-Induced Dyskinesias Amantadine is a well-established antiparkinsonian drug with multimodal dopaminergic and non-dopaminergic properties including an antagonistic effect on N -methyl-d-aspartate (NMDA) glutamate receptors [13]