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(2) Reactive oxygen species affects NP by mediating central sensitization, which is an increase in sensitivity to peripheral afferents in spinal pain-associated conductance neurons after NP develops

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Fumel B, Guerquin M-JLG, Staub C, Magistrini M, Gauthier C, Flamant F, Guillou F, Fouchcourt S: Thyroid hormone limits postnatal Sertoli cell proliferation in vivo by activation of its alpha1 isoform receptor (TR1) present in these cells and by regulation of Cdk4/JunD/cmyc mRNA levels in mice