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Administration of sesamin prior to MPTP exposure significantly reduced oxidative stress in the mouse brain: it suppressed the production of ROS and prevented the induction of iNOS and IL-6 in activated microglial cells (66)

Abnormal copper accumulation may alter the stability of the mitochondrial membrane, disrupt the redox balance within the mitochondria, and result in decreased intracellular energy production (Ruiz et al., 2021)

This anti-inflammatory effect may also alleviate symptoms of problematic skin conditions like the aforementioned rosacea, which causes redness, irritation, and inflammation of the skin

Kermagoret, A