foxo4 dri peptide senolytic 2023 study Molecular modelling of the FOXO4-TP53 interaction to design peptides for the elimination of senescent cancer The disordered p53 transactivation domain
The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications Frontiers Senolytic Peptide FOXO4 DRI Selectively Removes Senescent Cells From in vitro Expanded Human Chondrocytes Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging PMC Development of a novel senolytic by precise disruption of FOXO4 p53 complex eBioMedicine
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