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In the pursuit of optimal health and well-being, various wellness practices have gained popularity, and B12 injections have emerged as a notable contender

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Activated Parkin ubiquitinates outer mitochondrial membrane proteins including Mfn1, Mfn2, Miro1, and VDAC1 (Tanaka et al., 2010), followed by PINK1-mediated phosphorylation of these ubiquitinated substrates to amplify polyubiquitin chain signaling (Turco et al., 2021)

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