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Furthermore, dietary fiber reverses skeletal muscle wasting by inhibiting Atrogin-1, MuRF1, and autophagy markers such as LC3 and Bnip3

The gut microbiota contributes to host metabolism and protects against pathogens, thereby affecting directly or indirectly host physiological functions ( Collinsella belongs to the family Coriobacteriaceae and the phylum Actinobacteria

In line with the covalent binding mechanism, in vitro and cell-based thermal-shift assays showed that C1-27 induced a negative shift in the melting temperature indicating protein destabilization on binding (Supplementary Figs 11 and 15)

10.1111/ppl.12032 [Epub ahead of print]