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FIGURE 8 4 Discussion For pure glucocorticoid action, the synthetic glucocorticoid dexamethasone (DEX) outperforms natural cortisol and corticosterone ( In this study, administering dexamethasone (DEX) at a dose of 10 g/kg/day for 4 weeks led to a noticeable suppression of food intake (FI) and a decline in body weight gain (BWG) in rats