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chronic liver disease and hepatitis may present with elevated levels Renal impairment : Reduced clearance can contribute to accumulation, though this is rarely clinically significant Solid tumours : Certain malignancies, particularly hepatocellular carcinoma and metastatic disease, may elevate B12 levels [3] Evidence suggests that unexplained markedly elevated B12 levels without supplementation may sometimes be associated with underlying disease

Injection means subcutaneous self-administration, which bypasses the digestive system and can affect bioavailability - particularly for nutrients like B12 where absorption varies significantly between individuals

We have only been able to recruit 6 people from our membership base of over 7,000 who manage well on their three-monthly regime

A SARS-CoV-2 spike ferritin nanoparticle vaccine is protective and promotes a strong immunological response in the cynomolgus macaque coronavirus disease 2019 (COVID-19) Model