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Basic research plays a central role in the medical research cycle (see Figure 5 )

Similar content being viewed by others Introduction Approximately one in five cases of familial amyotrophic lateral sclerosis (fALS) is due to naturally occurring mutations in the gene encoding superoxide dismutase 1 (SOD1) 1

Unlike many drugs that simply block or force a pathway, these peptides were designed as bioregulators. They are analogs of molecules naturally found in the body that are based on an immune peptide called tuftsin, which is derived from a hormone fragment known as ACTH

Arendt-Nielsen L, Morlion B, Perrot S, Dahan A, Dickenson A, Kress HG, et al