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HIF-1 plays a key role in treatment resistance, particularly in radiotherapy, by activating antioxidant systems that mitigate ROS-induced DNA damage

Genome-wide DNA methylation differences between late-onset Alzheimers disease and cognitively normal controls in human frontal cortex

UA was able to ameliorate 6-OHDA-induced behavioral deficits and dopaminergic neuron loss by interfering with Akt inhibition and GSK-3 activation [171]

Excessive lipid uptake leads to the formation of foamy macrophages, inhibits their migratory capacity and traps them in the intima, ultimately leading to the induction of macrophage apoptosis and amplification of chronic inflammation (Moore et al., 2013)