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[ref] The glutamate-cysteine ligase (GCL) enzyme interacts with glutamate and cysteine, resulting in the formation of gamma-glutamylcysteine

Preclinical studies that are focused on promoting eosinophil apoptosis support continued investigations into sialic acid-binding immunoglobulin-like lectin 8 (SIGLEC-8)-targeted therapies, as engagement of SIGLEC-8 results in selective apoptosis of eosinophils