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This process requires a significant amount of energy and produces its own metabolic byproducts

10.1016/j.tim.2022.02.006 [DOI] [PubMed] [Google Scholar] Mateo P, Bonilla I, Fernandez-Valiente E, & Sanchez-Maeso E (1986)

In 2023, many popular peptides were placed in Category 2 substances for which the FDA has identified significant safety concerns effectively restricting their compounding