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Description

For rescue construct cloning, TFG human codon-optimized cDNA (WT, R22W, R106C, P285L, LIR2 mutant, LIR3 mutant, double LIR mutant, deltaPB1 and deltaCC

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Activation of the AMPA receptor (AMPAR) is necessary to induce membrane depolarization, which is responsible for removing Mg 2+ -mediated inhibition of the NMDAR channel

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More recently, the field has also attempted to tackle rarer genetic disorders such as FRDA

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However, its noteworthy that in 40-60% of HCC cases, there are no mutations in CTNNB1, Axin1, or Axin2 (65)

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