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Patients dealing with stiffness, reduced range of motion, or ongoing joint discomfort may consider whether this type of support fits into their recovery goals

In rats with acute myocardial ischemiareperfusion injury, elevated plasma Hcy induced mitochondrial dysfunction and oxidative stress through increased cytochrome c release, stimulation of ROS production, and ERK1/2 signaling pathway that subsequently caused cardiac dysfunction [66]

Data availability The proteomic data analyzed in this study are available at figshare ( Proteomics data and protein mapping to UniProt identifiers and gene names were provided by Sinotech Genomics Co., Ltd

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