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In each case, elevated Ms4a15 mRNA expression (~20-fold increase) robustly increased viability similar to the level of control cells treated with -tocopherol (Toc), an inhibitor of ferroptosis [34, 35]

A high dose of 1 gr/kg or between 60 to 100 mg/day as a single daily morning dose for an initial period of 3 to 4 weeks has been preferable

The cellular response to oxidative stress involves a complex network of signaling pathways that orchestrate defense mechanisms, repair processes and at times cell death (6)