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Such an approach might be particularly useful in smokers or diabetic patients with high oxidative burdens

Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization

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In animal models, upregulation of central -opioid receptors as a response to decreased endogenous opioids leads to increased sensitivity to the neuroinhibitory effects of exogenous opioids [11]