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Peter de Keizer's pioneering research at Erasmus University Medical Center to its current status as a leading senolytic research tool, FOXO4-DRI demonstrates how precise molecular targeting can enable selective elimination of harmful cellular populations while preserving healthy tissue function

2.7 Cell culture Human umbilical vein endothelial cells (HUVECs) purchased from Sigma Aldrich (Saint Louis, United States) were used for the experiment