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While p16 ink4a and SA--Gal are widely used in aging studies, emerging evidence suggests that p21 (a cyclin-dependent kinase inhibitor) may be a more robust marker of senescence in human kidney disease, particularly in contexts of chronic injury and fibrosis (Knoppert et al., 2023

Effects of vitamin A on survival in patients with chronic myelogenous leukemia: a SWOG randomized trial

When they're discharged, he sees them in follow-up himself, not a rotating physician

Erythrocytes dont have the intrinsic apoptotic machinery upstream of caspase-3, including cytochrome c or apoptotic peptidase-activating factor 1 (APAF-1) [22, 23]