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human kidney, but not rat, can form morphine3glucuronide

10.1161/CIRCULATIONAHA.117.032626 [DOI] [PMC free article] [PubMed] [Google Scholar] Walker MA, Chen H, Yadav A, et al

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Host drug-metabolizing enzyme expressions decrease toward the ileum and colon, whereas microbial density increases from approximately 1010 cells/g in the proximal small intestine to 1010 cells/g in the distal ileum and 1010 cells/g in the colon 104,105