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For a very long time, scientists thought that migraines were caused by changes in the blood flow to the brain

The authors administered 70 and 100 mg/kg doses of ferulic acid and reported that both of the doses significantly reduced seizure scores, myoclonic jerks, and cognitive decline

Moreover, omega-3 polyunsaturated fatty acids (n-3 PUFAs), particularly EPA and DHA, are proposed to ameliorate or prevent various mental and neurodegenerative disorders by modulating neuroimmune and apoptotic pathways

Other mechanisms Structural damage to the colon in IBD leads to increased intestinal epithelial permeability, a hallmark feature of colitis