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This decline leads to health problems like cognitive issues and metabolic disorders, which makes people think about ways to keep their NAD+ at good levels

Individuals most likely to benefit include: Those with pernicious anemia People with gastrointestinal disorders (e.g., Crohns disease, celiac disease, chronic gastritis) Patients following bariatric (weight loss) surgery Older adults with absorption difficulties Strict vegetarians or vegans at risk for deficiency People taking medications that can decrease vitamin B12 levels Laboratory testing usually confirms B12 deficiency before starting injections

Liu et al., 2021)

Molecular Profiles at a Glance Before comparing mechanisms, it helps to see the two peptides described by their basic chemical identities