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In randomized controlled trials in people living with HIV and central fat accumulation, tesamorelin produced clinically meaningful reductions in visceral adipose tissue in a majority of patients and was associated with improvements in liver enzymes when deep abdominal fat decreased

It is studied in preclinical models to investigate NNMTs role in metabolic regulation, NAD+ metabolism modulation, mitochondrial function effects, and potential metabolic benefits

Some people notice reduced appetite almost immediately

This causes the existing red blood cells in your bone marrow to become fragile and exceptionally large