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Mean NADP+ ( A ) and NADPH ( B ) levels in A549shNRF2-BIND-luc cells treated with water (Control) or 2.5 ng/mL doxycycline (Dox) for 48 h

The pathogenesis of PD has been strongly linked to several genetic factors, such as SNCA, LRRK2, DJ-1, PRKN (Parkin), PINK1, and GBA, underscoring the complex genetic underpinnings of the disease ( accessed on 15 January 2024)