David Sinclairs Complete Supplement List in 2025 Nicotinamide Mononucleotide (NMN): 1 gram daily Resveratrol: 1 gram daily with yogurt Spermidine: 1-2 mg daily Fisetin: 500 mg daily Vitamin D3: 4,000-5,000 IU daily Vitamin K2: 180-360 mcg daily Trimethylglycine (TMG/Betaine): 500-1,000 mg daily Omega-3 Fish Oil: Dosage not specified L-Taurine: 2 grams daily CoQ10: Dosage not specified in recent sources Metformin: 800-1,000 mg in the evening Low-Dose Aspirin: 83 mg daily Rapamycin: Dosage not publicly disclosed The sections that follow will explore each supplement in detail, covering how they work, the evidence behind them, and practical considerations for anyone interested in longevity
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49 Oder W, Grimm G, Kollegger H, Ferenci P, Schneider B, Deecke L
