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383,384 The secondary mtDNA depletion may exacerbate OXPHOS disturbance, increasing the production of mtROS

Almanza A, Carlesso A, Chintha C, Creedican S, Doultsinos D, Leuzzi B, Lus A, McCarthy N, Montibeller L, More S, Papaioannou A, Pschel F, Sassano ML, Skoko J, Agostinis P, de Belleroche J, Eriksson LA, Fulda S, Gorman AM, Healy S et al (2019) Endoplasmic reticulum stress signalingFrom basic mechanisms to clinical applications

Many hypertensive patients also have metabolic syndrome

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