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At the same time different neural cells perform distinct functions: more that five hundred million years of nervous system evolution segregated neural cells into electrically excitable neurones responsible for input/output information transfer and information processing and electrically non-excitable neuroglia, 2,3,4 which provide homoeostatic support and defence of the nervous tissue

However, H3Q5 dopaminylation findings remain heterogeneous across drugs and experimental paradigms, and, notably, no studies to date have established a direct role for this modification in depressive pathology (Table 2)

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