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In the prefrontal cortex, 5-HT2A hypermethylation demonstrated a bidirectional regulatory effect, influencing treatment efficacy while also being modulated by medication (Abdolmaleky et al., 2006)

International incidence of psychotic disorders, 2002-17: a systematic review and meta-analysis

Environ Toxicol 31(7):782798 Prez R, Burgos V, Marn V, Camins A, Olloquequi J, Gonzlez-Chavarra I, Ulrich H, Wyneken U, Luarte A, Ortiz L (2023) Caffeic acid phenethyl ester (CAPE): biosynthesis, derivatives and formulations with neuroprotective activities

Copper influences over 4,000 genes, acting as an epigenetic modifier that reverses age-related gene expression suppressing inflammatory genes and increasing expression of genes involved in tissue regeneration