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Circadian misalignment may further potentiate CTGF overexpression, compounding fibrotic injury through sustained activation of profibrotic gene programs

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Abdel Latef A.A.H., Tran L.-S.P

BMC Biol 17(1):57

Abstract The leptomeninges present a challenging tumour microenvironment with cells receiving low levels of nutrients and oxygen from cerebrospinal fluid (CSF), however these metabolic constraints are yet to be exploited therapeutically