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Two days after transfection, half of the samples were collected for Western blot analysis of CHAC1 expression and the other half for glutathione assay

Besides, hepcidin seems to downregulate both TFR1 and DMT1 through an unknown mechanism

However, large-scale, long-term clinical trials are urgently needed to validate the efficacy and safety of such interventions

This implies that androgen activation in PC cells may contribute to mt-DNA mutations and aging-related processes by increasing ROS formation, which can damage DNA and perhaps influence the mutation rate in cells, including PC cells