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Another myokine, myostatin (MSTN), can cause muscle atrophy, but plasma Mstn concentrations negatively correlate with the development of the cachexia phenotype in colorectal or lung cancer patients

In descending order, the medications used included serotonin-norepinephrine reuptake inhibitors (used by 182 patients), gabapentin (155 patients), tricyclic antidepressants (134 patients), trazodone (59 patients), pregabalin (46 patients), muscle relaxants (45 patients), montelukast (26 patients), -blockers (21 patients), aripiprazole (12 patients), histamine 1 or histamine 2 blockers (11 patients), naltrexone (8 patients), amphetamine- or methylphenidate-based stimulants (8 patients), midodrine (7 patients), fludrocortisone (6 patients), non-amphetamine stimulants (4 patients), pyridostigmine (4 patients), -blockers (1 patient), and droxidopa (1 patient)

Efectos adversos : Experimentar los efectos adversos del producto genera nuseas, vmitos o dolores corporales

The exclusion criteria were: patients suffering from lung disease except extensive bronchiectasis, such as cystic fibrosis, and pulmonary fibrosis