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Antioxidant Defense: Copper ions within the peptide complex are hypothesized to exhibit superoxide dismutase-like activity, protecting cells from oxidative stress and environmental damage

Archived from the original on 2009-06-21

Common mechanisms of ferroptosis including iron overload, lipid peroxidation, GPX4 inhibition, and system Xc inhibition in obesity, which lead to decrease of GSH, increased ROS, and even ferroptosis

For example, a mitoprotection bundle for high-risk surgery might include: a) a sulforaphane-based supplement a day before surgery (to activate Nrf2 antioxidant responses), b) remote ischemic preconditioning during anesthesia induction (209), c) low-dose IL-1ra (anakinra) at start of reperfusion, d) postoperative Dexmedetomidine infusion, and e) high-protein nutrition with omega-3 fatty acids to support recovery