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These hallmarks of aging satisfy three conditions: (i) they become apparent with advancing age, (ii) experimentally perturbing them causes poor aging (iii) therapeutically intervening upon them prevents, delays or reverses aging phenotypes

Avoid repeated cycling between warm and cold temperatures, as thermal stress accelerates degradation

All fat can be removed by these types of procedures, but those who are significantly overweight may be disqualified from certain procedures due to their increased risk of complications (for example, anesthesia in a patient who is severely overweight should be avoided)

HOPDs would be required to link their EHR and PACS data to their chosen vendor's translation software to calculate the measure, which we estimate would require no more than 1 hour to complete