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During sepsis, pathogen invasion activates innate-immune sentinelsespecially macrophages and neutrophilswhich deploy reactive species such as superoxide (O), hydroxyl radical (OH), peroxynitrite (ONOO ) and hypochlorous acid (HOCl) to kill microbes (57)

doi: 10.1038/s41579-020-0438-4 63 YamadaTHinoSIijimaHGendaTAokiRNagataRet al

The established UPLS models confirm the ability of the developed system to quantify catecholamine neurotransmitters (dopamine, norepinephrine, epinephrine)