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An important process is nitric oxide inactivation through its reaction with superoxide radicals, which results in the formation of peroxynitrite ONOO

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Integrating tumor microenvironment and hypoxia: a bifunctional PET tracer as a paradigm of translational radiopharmacy By Maria Salgueiro Recent developments in radiopharmaceutical sciences increasingly demonstrate a shift from single-target imaging toward integrated molecular strategies capable of reflecting tumor heterogeneity