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MTP Press, Boston, 1985). Conjugated metabolites that are pharmacologically active are not often successfully developed into drugs, whereas there are many examples of active Phase I metabolites that become drugs

Vitamin B12 plays a foundational role in energy production, nervous system health, and red blood cell formation

That said, the NF-kB pathway inhibition demonstrated by GLP-1 receptor agonists is directly relevant to psoriasis pathogenesis

Sedative and hypnotic agents like zolpidem and hydroxyzine have been employed, though their benefits are tempered by potential side effects (31, 35, 39)