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The Two-Step Mechanism Richard L

10.1038/s41419-020-2618-6 116 KoppulaP.LeiG.ZhangY.YanY.MaoC.KondiparthiL.et al (2022)

66,67 In recent years, gene editing systems have been a biotechnological breakthrough, providing a strategy for the treatment of various diseases

Biosynthetic pathway of free heme The biosynthetic pathway of heme is divided into three modules in microorganisms, including 5-aminolevulinic acid (ALA), uroporphyrinogen (urogen) III, and heme synthetic modules (Fig