napqi and glutathione Acetaminophen metabolism NAPQI-mediated mitochondrial effects NAPQI - an overview |
NAPQI an overview ScienceDirect Topics Acetaminophen NAPQI Hepatotoxicity: A Cell Line Model System Genome Wide Association Study PMC 5 Antidote: NAC (N acetylcysteine) NAC replenishes glutathione, restoring the ability to detoxify NAPQI. It's lifesaving if given early. Example: Hospitals use NAC as the standard treatment for APAP overdose. First line treatment for acetaminophen overdose: A. Flumazenil B. Naloxone C. N acetylcysteine D. Sodium bicarbonate
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