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doi: 10.3389/fphar.2026.1776868 Received 28 December 2025 Revised 28 February 2026 Accepted 02 March 2026 Published 07 April 2026 Volume 17 - 2026 Edited by Yongsheng Chen, Jinan University, China Reviewed by Hamidreza Pazoki-Toroudi, Iran University of Medical Sciences, Iran Liping You, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, China Updates Copyright 2026 Wang, Jiang, Huang, Zhang, Qi, Xu, Sun and Liu

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Since the trigeminal nerve and its fibers are responsible for almost all sensations in the face, anything that creates a significant change in the mouth is a potential pain trigger

Almost all the time, an ACL tear is a worse injury than an MCL tear